OBSTETRICS

Discontinuing SSRIs or SNRIs during pregnancy was associated with nearly double the risk of mental health emergencies, according to a cross-sectional analysis of 3,983 women. While prepregnancy psychiatric visit rates were similar between groups, antidepressant discontinuation was linked to significantly higher emergency department visits for psychiatric indications, particularly during the first and ninth months of pregnancy. These findings highlight the maternal risks of routine antidepressant discontinuation and reinforce the importance of individualized risk–benefit counseling during pregnancy.

Persistent maternal thyroid dysfunction—especially when it spans multiple trimesters—significantly increases the risk of autism in children. A 2.68-fold rise in autism diagnoses was observed in cases where thyroid imbalance occurred both before and during pregnancy, underscoring the need for careful monitoring and timely treatment adjustments.