ENDOCRINOLOGY

The MOMENTUM study reveals that more than one-quarter of patients with resistant hypertension have underlying endogenous hypercortisolism. Often lacking classic phenotypic signs, this “lurking” endocrine driver highlights the critical need for routine biochemical screening and endocrinology referral in this high-risk population.

A pre-specified subgroup analysis of the VESALIUS-CV trial demonstrates that the PCSK9 inhibitor evolocumab significantly reduces major adverse cardiovascular events and all-cause mortality in high-risk patients with diabetes who do not have established atherosclerosis, supporting earlier and more intensive lipid-lowering therapy.

Persistent maternal thyroid dysfunction—especially when it spans multiple trimesters—significantly increases the risk of autism in children. A 2.68-fold rise in autism diagnoses was observed in cases where thyroid imbalance occurred both before and during pregnancy, underscoring the need for careful monitoring and timely treatment adjustments.

Metabolic syndrome raises Parkinson’s risk by 39%, especially with genetic predisposition.

GLP-1 drugs may raise rare optic risks but also protect against severe diabetic eye damage.

Children in rural areas may face a higher risk of developing type 1 diabetes due to reduced microbial exposure—supporting the hygiene hypothesis. Balancing outdoor play, animal contact & less sanitizer use may help train the immune system. #T1D #RuralHealth

A new EASO framework could reclassify 18.8% of U.S. adults, previously labeled overweight, as having obesity by considering BMI, waist-to-height ratio, and health issues.
This may raise care needs but enable earlier treatment and better outcomes.

#ObesityRedefined