The MOMENTUM study reveals that more than one-quarter of patients with resistant hypertension have underlying endogenous hypercortisolism. Often lacking classic phenotypic signs, this “lurking” endocrine driver highlights the critical need for routine biochemical screening and endocrinology referral in this high-risk population.
ENDOCRINOLOGY
- CardiologyENDOCRINOLOGYINTERNAL MEDICINE < class="penci-entry-title entry-title grid-title penci_grid_title">Hypercortisolism common in patients with resistant hypertension>
- CardiologyENDOCRINOLOGYTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Evolocumab cuts heart events in patients with diabetes but no CVD>
A pre-specified subgroup analysis of the VESALIUS-CV trial demonstrates that the PCSK9 inhibitor evolocumab significantly reduces major adverse cardiovascular events and all-cause mortality in high-risk patients with diabetes who do not have established atherosclerosis, supporting earlier and more intensive lipid-lowering therapy.
- ENDOCRINOLOGYOBSTETRICSPSYCHIATRY < class="penci-entry-title entry-title grid-title penci_grid_title">Thyroid imbalance in pregnancy linked to increased likelihood of autism.>
Persistent maternal thyroid dysfunctionโespecially when it spans multiple trimestersโsignificantly increases the risk of autism in children. A 2.68-fold rise in autism diagnoses was observed in cases where thyroid imbalance occurred both before and during pregnancy, underscoring the need for careful monitoring and timely treatment adjustments.
- ENDOCRINOLOGYINTERNAL MEDICINENeurologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Risk for Parkinsonโs disease increased with presence of metabolic syndrome components>
Metabolic syndrome raises Parkinsonโs risk by 39%, especially with genetic predisposition.
- ENDOCRINOLOGYOphthalmologyPHARMACOLOGY < class="penci-entry-title entry-title grid-title penci_grid_title">Although rare, GLP-1s tied to higher risk for eye complications>
GLP-1 drugs may raise rare optic risks but also protect against severe diabetic eye damage.
- ENDOCRINOLOGY < class="penci-entry-title entry-title grid-title penci_grid_title">Living in rural areas may elevate risk for developing type 1 diabetes>
Children in rural areas may face a higher risk of developing type 1 diabetes due to reduced microbial exposureโsupporting the hygiene hypothesis. Balancing outdoor play, animal contact & less sanitizer use may help train the immune system. #T1D #RuralHealth
- BARIATRICSCategoriesENDOCRINOLOGY < class="penci-entry-title entry-title grid-title penci_grid_title">New framework would reclassify many Americans with overweight as having obesity>
A new EASO framework could reclassify 18.8% of U.S. adults, previously labeled overweight, as having obesity by considering BMI, waist-to-height ratio, and health issues.
This may raise care needs but enable earlier treatment and better outcomes.#ObesityRedefined
