A retrospective study found higher nonvertebral osteoporotic fracture incidence in patients with gout than in matched patients with osteoarthritis or soft-tissue rheumatism, despite lower recorded use of bone-protective therapy.
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In the phase 3 LATITUDE Atlas trial, 36.5% of adults receiving investigational zasocitinib achieved complete psoriasis clearance at week 16, compared with 13.9% receiving deucravacitinib. The study also reported higher …
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A study of 13,331 adults receiving anthracycline-based cancer treatment found that cardioprotective prophylaxis was used in just 2.4% of patients with de novo AML and 1.1% with DLBCL, highlighting gaps …
- GastroenterologyHEPATOLOGYONCOLOGYTRANSPLANT MEDICINE
Liver Transplant for Colorectal Liver Metastases: Survival Outcomes
Liver transplantation was associated with 1-, 3-, and 5-year survival of 90.9%, 69.8%, and 48.9% in a selected US cohort with unresectable colorectal liver metastases. A separate meta-analysis reported pooled …
- ALLERGY AND IMMUNOLOGYNEWS/RESEARCHPulmonology
Depemokimab Improves Quality of Life in Uncontrolled Asthma
Twice-yearly depemokimab was associated with improvements in asthma symptoms, activity, and daily-life impact by week 4, with benefits sustained through 52 weeks in an analysis of 559 patients from the …
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The FDA approved a once-daily Zilbrysq autoinjector for eligible adults with generalized myasthenia gravis, offering an alternative to the prefilled syringe. Early studies reported bioequivalence and generally favorable device tolerability.
- NEWS/RESEARCHOphthalmologyPEDIATRICS
Essilor Stellest 2.0 Shows Early Myopia-Control Benefits in Children
Children wearing Essilor Stellest 2.0 lenses had less myopia progression and axial elongation after 6 months in interim trial results. Separate 2-year data support the original Stellest lens.
A review suggests PCOS/PMOS may be associated with cognitive impairment and dementia risk, but findings are inconsistent. Obesity and insulin resistance may contribute, and evidence does not currently support routine …
A study in JAMA Network Open found undeclared clobetasol propionate in 6 of 18 selected online skin products, raising concerns about hidden prescription drugs and consumer safety.
GastroenterologyNEWS/RESEARCHTRIALS
Subcutaneous Infliximab After a Drug Holiday in IBD: Study Findings
Subcutaneous infliximab helped patients with Crohnโs disease and ulcerative colitis regain or maintain disease control after an IV treatment interruption, with favorable outcomes reported regardless of antidrug antibody status.
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