This overview highlights emerging treatments for neovascular AMD, including new tyrosine kinase inhibitors and promising gene therapy programs. Clinical trials over the next two years may bring long-term, more durable treatment options for patients.
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CardiologyIMMUNOLOGYOphthalmology < class="penci-entry-title entry-title grid-title penci_grid_title">New technologies advance wet AMD treatment space>
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DERMATOLOGYIMMUNOLOGYRHEUMATOLOGY < class="penci-entry-title entry-title grid-title penci_grid_title">Enpatoran delivers robust skin lupus efficacy across CLE and SLE, achieving high CLASI responses and early IFN suppression in WILLOW trial>by chnfo@suni0by chnfo@suni0
The WILLOW trial reveals Enpatoran’s strong performance in mucocutaneous lupus, achieving high CLASI-50 and CLASI-70 response rates, remission milestones, and rapid IFN gene suppression in both CLE and SLE patients.
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DERMATOLOGYIMMUNOLOGYTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Brepocitinib may emerge as the first targeted treatment option for dermatomyositis.>
The phase 3 VALOR trial shows that brepocitinib significantly improves skin disease, muscle strength, and functional disability in adults with dermatomyositis. As the first modern targeted therapy to demonstrate positive results, brepocitinib may transform treatment options while reducing steroid reliance.
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Cardiology < class="penci-entry-title entry-title grid-title penci_grid_title">TAVR and surgery showed similar results at 7-year follow-up.>
SAN FRANCISCO — Seven-year follow-up data from the landmark PARTNER 3 trial have confirmed that transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) offer comparable long-term …
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Cardiology < class="penci-entry-title entry-title grid-title penci_grid_title">Tackling Cancer Pain Head-On>by chnfo@suni0by chnfo@suni0
[ad_ 1] A New Kind of Tumor Board: Tackling Cancer Pain Head-On.A pioneering multidisciplinary tumor board has been established with a singular focus — managing cancer-related pain, particularly that arising …
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Cardiology < class="penci-entry-title entry-title grid-title penci_grid_title">Discovery of new genetic link to osteosarcoma opens ‘window of opportunity’>
Key Points: Researchers have identified that inherited mutations in the SMARCAL1 gene are closely associated with an increased risk of osteosarcoma, the most common type of bone cancer in …
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A 16-week Mediterranean diet program significantly improved psoriasis severity and quality of life, independent of weight loss.
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Exercise, not liraglutide, reduced atherosclerosis after weight loss in adults with obesity, improving inflammation and heart health.
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CardiologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Olezarsen cut triglycerides by 60%>
Olezarsen cuts triglycerides up to 60%, normalizing levels in 85% of high-risk patients.
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CardiologyINTERNAL MEDICINETRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Baxdrostat delivers significant blood pressure reductions in patients with treatment-resistant hypertension.>
Baxdrostat lowers BP in resistant hypertension, offering a new treatment option.

