Key takeaways: Using NHANES data from 2017 to 2023, obesity prevalence in the U.S. is 75.2% when excess adiposity cutoffs are used. Among adults with a BMI of less …
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The FDA has granted approval to Novartis for Itvisma (onasemnogene abeparvovec-brve), the first gene replacement therapy for spinal muscular atrophy (SMA) available for patients aged 2 years and older. Backed by data from the Phase 3 STEER and Phase 3b STRENGTH trials, this one-time intrathecal treatment addresses the genetic root cause of SMA and is expected to be available in the U.S. this December.
Excerpt : Despite advances in technology, cardiovascular death rates remain stagnant. Interventional cardiologist Dr. Koushik Reddy argues for a radical paradigm shift—moving the foundation of care from the cath lab to the “kitchen table.” Learn how he uses the “CARROTS” framework to integrate lifestyle medicine into critical cardiac care.
Persistent maternal thyroid dysfunction—especially when it spans multiple trimesters—significantly increases the risk of autism in children. A 2.68-fold rise in autism diagnoses was observed in cases where thyroid imbalance occurred both before and during pregnancy, underscoring the need for careful monitoring and timely treatment adjustments.
This overview highlights emerging treatments for neovascular AMD, including new tyrosine kinase inhibitors and promising gene therapy programs. Clinical trials over the next two years may bring long-term, more durable treatment options for patients.
The phase 3 VALOR trial shows that brepocitinib significantly improves skin disease, muscle strength, and functional disability in adults with dermatomyositis. As the first modern targeted therapy to demonstrate positive results, brepocitinib may transform treatment options while reducing steroid reliance.
SAN FRANCISCO — Seven-year follow-up data from the landmark PARTNER 3 trial have confirmed that transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) offer comparable long-term …
Key Points: Researchers have identified that inherited mutations in the SMARCAL1 gene are closely associated with an increased risk of osteosarcoma, the most common type of bone cancer in …
A 16-week Mediterranean diet program significantly improved psoriasis severity and quality of life, independent of weight loss.
Exercise, not liraglutide, reduced atherosclerosis after weight loss in adults with obesity, improving inflammation and heart health.