The phase 3 VALOR trial shows that brepocitinib significantly improves skin disease, muscle strength, and functional disability in adults with dermatomyositis. As the first modern targeted therapy to demonstrate positive results, brepocitinib may transform treatment options while reducing steroid reliance.
TRIALS
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DERMATOLOGYIMMUNOLOGYTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Brepocitinib may emerge as the first targeted treatment option for dermatomyositis.>
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DERMATOLOGYTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Mediterranean diet could improve psoriasis symptoms>
A 16-week Mediterranean diet program significantly improved psoriasis severity and quality of life, independent of weight loss.
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CardiologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Exercise, but not liraglutide, linked to decreased atherosclerosis development>
Exercise, not liraglutide, reduced atherosclerosis after weight loss in adults with obesity, improving inflammation and heart health.
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CardiologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Olezarsen cut triglycerides by 60%>
Olezarsen cuts triglycerides up to 60%, normalizing levels in 85% of high-risk patients.
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CardiologyINTERNAL MEDICINETRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Baxdrostat delivers significant blood pressure reductions in patients with treatment-resistant hypertension.>
Baxdrostat lowers BP in resistant hypertension, offering a new treatment option.
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ENDOCRINOLOGYINTERNAL MEDICINENeurologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Risk for Parkinson’s disease increased with presence of metabolic syndrome components>
Metabolic syndrome raises Parkinson’s risk by 39%, especially with genetic predisposition.
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ANDROLOGYTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Oral testosterone therapy improves sexual activity for men>
Oral testosterone undecanoate (Jatenzo) boosted T levels & sexual function in 92% of hypogonadal men by day 105 in phase 3 trial.
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ORTHOPEDICSTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">Standardized protocol for PJI may lead to better outcomes>
A recent study presented at the Musculoskeletal Infection Society Annual Meeting (Aug. 1–2, 2025, Jersey City, N.J.) highlighted the benefits of implementing a standardized protocol for managing periprosthetic joint …
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CardiologyOphthalmologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">FDA Approves Lenz Therapeutics’ Vizzâ„¢ for Presbyopia Treatment>
FDA approves Vizz™—the first once-daily eye drop for presbyopia. Fast onset (30 mins), long-lasting (10 hrs), no myopic shift. Backed by CLARITY trials with 96% near-vision improvement. Designed for active lifestyles.
#EyeHealth #VizzDrop -
CategoriesNeurologyTRIALS < class="penci-entry-title entry-title grid-title penci_grid_title">MIND Diet and Dementia Risk Reduction>
🧠A major study shows the MIND diet may cut Alzheimer’s risk by up to 25%, with greatest benefit seen in those improving diet over time. Results vary by ethnicity, highlighting need for culturally adapted plans. #BrainHealth #MINDdiet

