Topline results from the Phase 3 REVEAL-1 trial demonstrate that subcutaneous elegrobart achieved rapid, clinically meaningful reductions in proptosis and diplopia in active Thyroid Eye Disease patients with convenient Q4W …
- DERMATOLOGYMICROBIOLOGY ADVANCEMENTSTRIALS
Brepocitinib โa major move forwardโ as first targeted therapy for dermatomyositis: VALOR
Brepocitinib, a novel oral TYK2/JAK1 inhibitor, demonstrated significant clinical efficacy in the phase 3 VALOR trial for dermatomyositis, achieving superior improvement scores, higher remission rates and meaningful reductions in corticosteroid …
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Recent empirical studies reveal that unregulated celebrity and influencer alcohol promotions on social media routinely bypass age restrictions, exposing millions of underage users to subtle drinking cues. This digital marketing …
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A retrospective cohort study from UCLA reveals that the sustained use of medications for alcohol use disorder (MAUD) for three months or longer is associated with significantly improved 1-year and …
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Updated results from the phase 1/2 Beamion LUNG-1 study, presented at the European Lung Cancer Congress, show that the HER2-targeted therapy zongertinib achieved a 76% objective response rate and a …
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- OBSTETRICSPSYCHIATRY
Antidepressant discontinuation during pregnancy raises risk for mental health emergencies
Discontinuing SSRIs or SNRIs during pregnancy was associated with nearly double the risk of mental health emergencies, according to a cross-sectional analysis of 3,983 women. While prepregnancy psychiatric visit rates …
A pre-specified subgroup analysis of the VESALIUS-CV trial demonstrates that the PCSK9 inhibitor evolocumab significantly reduces major adverse cardiovascular events and all-cause mortality in high-risk patients with diabetes who do …
The MetALD-ALD Prediction Index (MAPI) is a validated diagnostic tool that utilizes five routine biomarkers (sex, MCV, GGT, HDL, HbA1c) to distinguish metabolic from alcohol-associated steatotic liver disease, bypassing the …
A large UK Biobank analysis found that higher serum vitamin D levels were associated with a lower risk of hospitalization for respiratory tract infections, while severe deficiency increased risk. Although …